| Date | 1885 |
| Author | Ferran |
| Contribution | Attempted to control a cholera epidemic with an attenuated vaccine. |
| Reference | Foster |
| Notes | Haime Ferran y Clua. This appears to be the first attempt to extend to humans the use of a deliberately attenuated germ-culture, as introduced by Pasteur in the immunoprophylaxis of anthrax. Despite claims of success, Ferran's vaccine was not statistically validated and in the end was judged a failure. Ferran had tested his vaccine on himself and colleagues. According to Waller, Ferran refused to disclose essential information about his vaccine when approached by a foreign investigating team [a refusal that may or may not have been reasonable]. |
| Category | Immunology |
| Pathogen Class | Bacteria |
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