| Date | 1847 |
| Author | Dempster |
| Contribution | Used spleen enlargement as index in assessing malaria endemicity in children. |
| Reference | Bruce-Chwatt |
| Notes | An example of a pre-germ-theory physical index of infection (based on palpation). Cited in Bruce-Chwatt, Essential Malariology, 1980. |
| Category | Miscellany |
| Pathogen Class | Protozoa |
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