| Date | 1821 | 
| Author | Bretonneau | 
| Contribution | Presented oral reports on the specificity of diseases such as diphtheria and typhoid. | 
| Reference | Bullock | 
| Notes | A concept that was important ground work for development of the germ theory. Published in 1826-29. Bullock - p. 157. | 
| Category | Miscellany | 
| Pathogen Class | General | 
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