| Date | 1865 |
| Author | Pasteur |
| Contribution | a. Saw "corpuscular bodies" in silkworm disease. |
| Reference | Bullock |
| Notes | Worked for 5 years, discovering in 1867 that two diseases were involved: pebrine (now attributed to protozoon Nosema) and flacherie (now attributed to a virus that predisposes to a bacillus). Later, Pasteur attached significance to this work in the context of the germ theory, especially the observation of "germ corpuscles" or spores in his original papers. Note from Carter: This was the beginning of Pasteur's studies on silkworm disease. He confirmed the known observation that such bodies were often seen in dead worms. Some considered them to be the causative "parasite." |
| Category | Miscellany |
| Pathogen Class | General |
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