| Date | 1893 |
| Author | Haffkine |
| Contribution | Used an attenuated vaccine to control cholera in India. |
| Reference | Bibel |
| Notes | The vaccine was based on guinea pig studies and attenuation was by aeration of bacterial cultures. Haffkine tested it on himself and a few friends, and used it on more than 40,000 people in India. While not rigorously controlled, this field trial probably represents the first reasonably successful anti-bacterial vaccine used in humans. Not mentioned in Garrison 4th Ed. The Haffkine story is told in "The Story of Dr. Haffkine" by Mark Popovsky, published (without date but evidently during the Soviet era) by Progress Publishers, Moscow; translated from the Russian by Vezey; with photographs. [W.C.C. coll.] |
| Category | Immunology |
| Pathogen Class | Bacteria |
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