| Date | 1892 |
| Author | Iwanowski |
| Contribution | Reported that sap of plant with tobacco mosaic disease was infective even after bacteriological filtration. |
| Reference | Lechevalier |
| Notes | Suspected faulty filter or disease caused by soluble toxin (a reasonable conclusion because the diphtheria toxin had already been reported, see 1888). From a translation of part of his report (Lechevalier) it would seem that he did not suspect a class of smaller pathogens. Nevertheless, his illustrations depict "inclusion bodies" (aggregates of virions) and crystals of the virus. |
| Category | Causation |
| Pathogen Class | Viruses |
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