| Date | 1680 |
| Author | Leeuwenhoek |
| Contribution | Observed and recorded what were probably parasitic protozoa, in gut of horse-fly. |
| Reference | Foster |
| Notes | Letter (in Dutch) of 12 November, 1680; published in part, in English, in 1681; see Dobell, 1932. The organisms were probably trypanosomes in a vector tabanid fly. This appears to be the first record of a parasitic protozoon. |
| Category | Microscopy |
| Pathogen Class | Protozoa |
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