| Date | 1891 |
| Author | Ehrlich |
| Contribution | a. Reported methylene blue effective against malaria in humans. |
| Reference | Lechevalier |
| Notes | Based on greater intensity of staining of parasites as compared to blood cells in vitro. The dye was given to two patients and allegedly gave rapid cure. (This may be the first test of a systemic synthetic drug in a human infectious disease, preceding, the first trials of arsenicals against trypanosome infections.) |
| Category | Miscellany |
| Pathogen Class | Protozoa |
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