| Date | 1881 |
| Author | Pasteur |
| Contribution | a. Reported immunization against anthrax by attenuated bacteria. |
| Reference | Geison |
| Notes | In February Pasteur announced his anthrax vaccine. The public demonstration was held in June; see other entry for same year. See English translation in Brock 1961. Pasteur linked his anthrax vaccine to his earlier fowl cholera vaccine, implying that both were based on attenuation by aging in air (exposure to atmospheric oxygen). For anthrax, he found it necessary to use spore-free cultures, obtainable by culture at 42-43 C. Geison reviews this situation in depth; concludes that this was not the vaccine actually used for public demonstration. |
| Category | Immunology |
| Pathogen Class | Bacteria |
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