Details

Date1881
AuthorPasteur
Contributiond. Reported transmission of rabies by intracranial inoculation of brain tissue.
ReferenceGeison
NotesThis was his first paper on rabies, apart from a false-start note in the previous year. The advance was made by his colleague Roux, and involved drilling a hole in the skull of recipient dogs and transferring brain material from rabid dogs onto the brain of recipient dogs. This gave more reliable infections and a shorter prepatent period. Note from another source: Pasteur extended work of Galtier by transmitting rabies from dogs to rabbits not only by means of saliva but also by spinal cord.
CategoryCausation
Pathogen ClassViruses

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