| Date | 1881 |
| Author | Pasteur |
| Contribution | d. Reported transmission of rabies by intracranial inoculation of brain tissue. |
| Reference | Geison |
| Notes | This was his first paper on rabies, apart from a false-start note in the previous year. The advance was made by his colleague Roux, and involved drilling a hole in the skull of recipient dogs and transferring brain material from rabid dogs onto the brain of recipient dogs. This gave more reliable infections and a shorter prepatent period. Note from another source: Pasteur extended work of Galtier by transmitting rabies from dogs to rabbits not only by means of saliva but also by spinal cord. |
| Category | Causation |
| Pathogen Class | Viruses |
Copyright © 2007- William C. Campbell. All rights reserved.