| Date | 1875 | 
| Author | Losch | 
| Contribution | Reported amebae as almost certain cause of severe dysentery in a human. | 
| Reference | Ackerknecht | 
| Notes | Also spelled Loesch. See book by Kean, Mott and Russell. Successfully transmitted the infection to a dog. Detailed description of disease and pathogen. Exceedingly cautious and correct, in saying that dysentery might, on the evidence he had, have been merely a predisposing factor leading to massive invasion of colon tissue by amebae. | 
| Category | Causation | 
| Pathogen Class | Protozoa | 
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